| Bioactivity | TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice[1]. |
| Target | TMPRSS6 (Matriptase-2) |
| Name | TMPRSS6-IN-1 |
| CAS | 2088415-78-3 |
| Formula | C33H40N8O4S2 |
| Molar Mass | 676.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. St-Georges C, et al. Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids. Eur J Med Chem. 2017 Mar 31;129:110-123. |
TMPRSS6-IN-1
CAS: 2088415-78-3 F: C33H40N8O4S2 W: 676.85
TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine prot
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