| Bioactivity | TLX agonist 2 (compound 31) is a TLX agonist (EC50=0.1 μM; Kd=0.16 μM). TLX agonist 2 promotes TLX transcriptional activity and enhances the expression of TLX target genes by binding to TLX. TLX agonist 2 can be used in the study of neurodegenerative diseases[1]. |
| Formula | C23H18F3N5O2 |
| Molar Mass | 453.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hank, et al. "Development of tailless homologue receptor (TLX) agonist chemical tools." Journal of Medicinal Chemistry (2024). |