TLR7/8/9-IN-1_product_DataBase

CAS: 2180127-82-4 F: C27H37N3O2 W: 435.60

TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9).
Name	TLR7/8/9-IN-1
CAS	2180127-82-4
Formula	C27H37N3O2
Molar Mass	435.60
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Mussari CP, et al. Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). ACS Med Chem Lett. 2020 Jul 29;11(9):1751-1758.

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