| Bioactivity | TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1]. |
| Name | TLR7 agonist 14 |
| CAS | 2832199-45-6 |
| Formula | C29H36N6O3 |
| Molar Mass | 516.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Emma G DeYoung, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5- c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368. |
TLR7 agonist 14
CAS: 2832199-45-6 F: C29H36N6O3 W: 516.63
TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces t
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