| Bioactivity | TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM. | ||||||||||||
| Name | TLR7 agonist 1 | ||||||||||||
| CAS | 2178156-33-5 | ||||||||||||
| Formula | C21H25N5O | ||||||||||||
| Molar Mass | 363.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Pieters S, et al. Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists. Bioorg Med Chem Lett. 2018 Feb 15;28(4):711-719. |