| Bioactivity | TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability[1]. |
| Target | IC50: 8 nM (TNIK), 4.7 μM (hERG), 6.3 μM (β-lactamase) |
| Name | TINK-IN-1 |
| CAS | 1417795-25-5 |
| Formula | C24H24N4O3 |
| Molar Mass | 416.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ho KK, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. |
TINK-IN-1
CAS: 1417795-25-5 F: C24H24N4O3 W: 416.47
TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM
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