| Bioactivity | THRX-194556 is a 5-HT4 receptor agonist. THRX-194556 can be used to study gastrointestinal functional disorders and Alzheimer’s disease[1][2]. |
| CAS | 886579-13-1 |
| Formula | C28H41N5O5S |
| Molar Mass | 559.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. A Multivalent Approach to the Design and Discovery of Orally Efficacious 5-HT4 Receptor AgonistsJ. Med. Chem., 2009, 52 (17), pp 5330-5343 [2]. Long DD, et al. Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT(4) receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6048-52. [3]. Long DD, Armstrong SR, Beattie DT, Choi SK, Fatheree PR, Gendron RA, Goldblum AA, Humphrey PP, Marquess DG, et al. Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: clinical compound TD-2749. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4849-53. |
THRX-194556
CAS: 886579-13-1 F: C28H41N5O5S W: 559.72
THRX-194556 is a 5-HT4 receptor agonist. THRX-194556 can be used to study gastrointestinal functional disorders and Alzh
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