| Bioactivity | TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9.8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research[1]. |
| Invitro | TH470 (0.05-5 μM; 12 h) inhibits the growth of neurite[1]. Cell Viability Assay[1] Cell Line: |
| Name | TH470 |
| CAS | 2834739-51-2 |
| Formula | C30H31N5O5S2 |
| Molar Mass | 605.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hanke T, et al. Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J Med Chem. 2022 Oct 13;65(19):13264-13287. |