| Bioactivity | TFMU-ADPr ammonium is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr ammonium can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr ammonium has excellent reactivity, generality, stability, and usability. TFMU-ADPr ammonium is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes[1]. |
| Name | TFMU-ADPr ammonium |
| Formula | C25H29F3N6O16P2 |
| Molar Mass | 788.47 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Drown BS, et al. Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chem Biol. 2018 Dec 20;25(12):1562-1570.e19. |
TFMU-ADPr ammonium
CAS: F: C25H29F3N6O16P2 W: 788.47
TFMU-ADPr ammonium is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr ammo
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