| Bioactivity | TEAD-IN-9 is a TEAD1 inhibitor with an IC50 of 0.29 μM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD (WO2024061366A1; compound 17)[1]. |
| In Vivo | 在 SD 大鼠的药代动力学分析[1] Route |
| Formula | C23H23F3N3O3P |
| Molar Mass | 477.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dong Liu. Small molecule compound having phosphorylated aryl structure, and use thereof. WO2024061366A1. |