| Bioactivity | TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | ||||||||||||
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | ||||||||||||
| Name | TCO-PEG4-NHS ester | ||||||||||||
| CAS | 1613439-69-2 | ||||||||||||
| Formula | C24H38N2O10 | ||||||||||||
| Molar Mass | 514.57 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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TCO-PEG4-NHS ester
CAS: 1613439-69-2 F: C24H38N2O10 W: 514.57
TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavab
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