| Bioactivity | TCF199 is an allosteric stabilizer that stabilizes the 14-3-3/TAZ peptide interaction, binding to the 14-3-3ζ/E R α peptide and 14-3-3ζ/Chibby peptide. TCF199 has a Kd value of 122 μM for its interaction with 14-3-3/TAZ[1]. |
| Formula | C17H24N2O2 |
| Molar Mass | 288.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Blaž Andlovic, et al. Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction. Biochemistry. 2024 Sep 3;63(17):2196-2206. |