| Bioactivity | TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins[1]. |
| Invitro | TAT (YGRKKRRQRRR) represents amino acids 47-57 of the human immunodeficiency virus type I (HIV-1) TAT protein. The positively charged protein transduction domain of the HIV-1 TAT protein (TAT-PTD; residues 47-57 of TAT) rapidly translocates across the plasma membrane of living cells. TAT (YGRKKRRQRRR; TAT-PTD) can cross the hydrophobic lipid bilayer of a cell membrane simply by passive diffusion[1]. |
| Name | TAT |
| CAS | 191936-91-1 |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg |
| Shortening | YGRKKRRQRRR |
| Formula | C64H118N32O14 |
| Molar Mass | 1559.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |