| Bioactivity | TAT-SAMβA is the peptide consist of RNAENFDRF (SAMβA; HY-P3429) conjugated to the cell penetrating TAT protein-derived peptide TAT47–57. TAT-SAMβA is a selective antagonist of Mfn1-βIIPKC association. TAT-SAMβA protects mouse embryonic fibroblast cells (MEFs) against oxidative stress-induced cytotoxicity[1]. |
| Target | Mfn1-βIIPKC association |
| Name | TAT-SAMβA |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Arg-Asn-Ala-Glu-Asn-Phe-Asp-Arg-Phe |
| Shortening | YGRKKRRQRRRGGRNAENFDRF |
| Formula | C118H195N51O31 |
| Molar Mass | 2824.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ferreira JCB, et al. A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nat Commun. 2019 Jan 18;10(1):329. |