| Bioactivity | TAT-QFNP12 block the NDRG2-PPM1A binding and reduce Smad2/3 phosphorylation, decreased astrocytic MMP-9 production and BBB disruption after subarachnoid hemorrhage (SAH)[1]. |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Val-Lys-Lys-Glu-Ala-Glu-Leu-Asp-Lys-Tyr-Leu-Glu |
| Shortening | YGRKKRRQRRRVKKEAELDKYLE |
| Formula | C130H225N47O35 |
| Molar Mass | 3006.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng D, et al. Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage. Sci Adv. 2022 Sep 30;8(39):eabq2423. |