| Bioactivity | TAT-CBD3, a 15-amino acid peptide from CRMP2, fused to the TAT cell-penetrating motif of the HIV-1 protein, disrupts CRMP2-NMDAR interaction without change in NMDAR localization[1]. |
| Invitro | TAT-CBD3 (10 μM) 抑制NMDAR并减轻谷氨酸诱导的Ca2+ 失调。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> TAT-CBD3 相关抗体: |
| CAS | 1355359-36-2 |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Arg-Ser-Arg-Leu-Ala-Glu-Leu-Arg-Gly-Val-Pro-Arg-Gly-Leu |
| Shortening | YGRKKRRQRRRARSRLAELRGVPRGL |
| Formula | C134H243N59O32 |
| Molar Mass | 3192.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tatiana Brustovetsky, et al. Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity. J Biol Chem. 2014 Mar 14;289(11):7470-82. |
TAT-CBD3
CAS: 1355359-36-2 F: C134H243N59O32 W: 3192.74
TAT-CBD3, a 15-amino acid peptide from CRMP2, fused to the TAT cell-penetrating motif of the HIV-1 protein, disrupts CRM
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