TAT-BH4 (Bcl-xL) (TFA)_product_DataBase

Bioactivity	TAT-BH4 (Bcl-xL) TFA is localized mainly at the mitochondria, prevents apoptotic cell death. TAT-BH4 (Bcl-xL) TFA contains the N-terminal eosin-labeled cysteine plus the protein transduction domain of HIV TAT protein (amino acids 49 to 57) fused to the Bcl-xL BH4 peptide. TAT-BH4 TFA can be used for research of diseases caused by accelerated apoptosis[1].
Name	TAT-BH4 (Bcl-xL) (TFA)
Sequence	Ac-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-{βAla}-Ser-Asn-Arg-Glu-Leu-Val-Val-Asp-Phe-Leu-Ser-Tyr-Lys-Ser-Gln-Lys-Gly-Tyr-Ser
Shortening	Ac-GRKKRRQRRR-{βAla}-SNRELVVDFLSYKSQKGYS
Formula	C159H268N58O45.xC2HF3O2
Molar Mass	3712.19 (free acid)
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Shimizu S, et al. BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3100-5.

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