Bioactivity | TASP0376377 is a potent and selective CRTH2 antagonist (IC50: 13 nM). TASP0376377 has binding affinity for CRTH2 (IC50: 19 nM)[1]. |
Name | TASP0376377 |
CAS | 1233246-60-0 |
Formula | C25H16Cl2N2O4 |
Molar Mass | 479.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nishikawa-Shimono R, et al. Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. Bioorg Med Chem. 2013 Dec 15;21(24):7674-85. |