| Bioactivity | TAK-756 is a TAK1 inhibitor with good selectivity for IRAK1/4 and excellent intra-articular pharmacokinetic properties. TAK1 is a potential molecular target for osteoarthritis (OA) with complementary anti-catabolic and anti-inflammatory effects[1]. |
| Formula | C25H25N3O5 |
| Molar Mass | 447.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Langlois JB, et al. Identification of TAK-756, A Potent TAK1 Inhibitor for the Treatment of Osteoarthritis through Intra-Articular Administration. J Med Chem. 2024 Dec 12;67(23):21163-21185. |