Bioactivity | TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1]. |
Name | TAK 044 |
CAS | 157380-72-8 |
Sequence | cyclo({d-Asp}-{α-amino-γ-oxo-4-phenyl-1-piperazinebutanoyl-Asp}-Asp-{d-(2-thienyl)glycine}-Leu-{d-Trp}) (disodium salt) |
Shortening | cyclo({d-Asp}-{α-amino-γ-oxo-4-phenyl-1-piperazinebutanoyl-Asp}-D-{d-(2-thienyl)glycine}-L-{d-Trp}) (disodium salt) |
Formula | C45H51N9Na2O11S |
Molar Mass | 971.98 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Toshifumi Watanabe, et al. TAK-044: An Endothelin Receptor Antagonist. , 14(1), 36–46. |