TAK-041_product_DataBase

CAS: 1929519-13-0 F: C18H15F3N4O3 W: 392.33

TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of ne

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia[1].

In Vivo

TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice[1]. Animal Model:

Name

TAK-041

CAS

1929519-13-0

Formula

C18H15F3N4O3

Molar Mass

392.33

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia [published online ahead of print, 2021 Jul 14]. J Med Chem. 2021;10.1021/acs.jmedchem.1c00820.

PeptideDB

TAK-041

CAS: 1929519-13-0 F: C18H15F3N4O3 W: 392.33