| Bioactivity | T3 Peptide is an active fragment of tumstatin. T3 Peptide binds integrin αvβ3/αvβ5, activates the PI3K/Akt/p70S6K signaling pathway, and thus stimulates the proliferation and migration of rat cardiac fibroblasts[1]. |
| Sequence | Leu-Gln-Arg-Phe-Thr-Thr-Met-Pro-Phe-Leu-Phe-Cys-Asn-Val-Asn-Asp-Val-Cys-Asn-Phe (Disulfide bridge: Cys12-Cys18) |
| Shortening | LQRFTTMPFLFCNVNDVCNF (Disulfide bridge: Cys12-Cys18) |
| Formula | C109H159N27O29S3 |
| Molar Mass | 2407.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yasuda J, et al., T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2017 Nov;390(11):1135-1144. |