| Bioactivity | T100-Mut is a cell-permeable peptide whose N-terminus is conjugated with a myristoylated group, allowing it to penetrate and localize to the intracellular side of the plasma membrane, thus mimicking the topology of Tmem100-3Q. T100-Mut can alleviate TRPA1-mediated pain[1]. |
| Sequence | {Myr}-Trp-Lys-Val-Arg-Gln-Arg-Asn-Lys-Lys-Val-Gln-Gln-Gln-Glu-Ser-Gln-Thr-Ala-Leu-Val-Val-Asn-Gln-Arg-Cys-Leu-Phe-Ala |
| Shortening | {Myr}-WKVRQRNKKVQQQESQTALVVNQRCLFA |
| Formula | C161H271N49O42S |
| Molar Mass | 3597.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Weng HJ, et al. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46. |