| Bioactivity | T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity[1]. |
| Invitro | T01-1 (0-50 nM; 3 days) anti-proliferative activity in HCC1806 cells[1]. Cell Proliferation Assay[1] Cell Line: |
| In Vivo | T01-1 (1 mg/kg; i.v.; single) shows T1/2 values of 2.78 and 1.97 h in female and male rats, respectively[1]. Animal Model: |
| Name | T01-1 |
| CAS | 2356229-14-4 |
| Formula | C26H29N3O6S |
| Molar Mass | 511.59 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Li Deliang, et al. Camptothecin derivative and water-soluble prodrug, pharmaceutical composition preparation method, and application. Patent WO2020156189A1. |