| Bioactivity | T-3256336 is a potent and orally active cIAP1 and XIAP inhibitor with IC50s of 1.3, 200 nM, respectively. T-3256336 shows anti-tumor activity[1]. |
| In Vivo | T-3256336 (compound 45) (30, 100 mg/kg; p.o.) 增加 caspase-3/7 活性并在小鼠中显示抗肿瘤活性[1]。 Animal Model: |
| Name | T-3256336 |
| CAS | 1266227-69-3 |
| Formula | C31H45F2N5O5 |
| Molar Mass | 605.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hashimoto K, et al. Design and synthesis of potent inhibitor of apoptosis (IAP) proteins antagonists bearing an octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline mimetic. J Med Chem. 2013 Feb 14;56(3):1228-46. |
T-3256336
CAS: 1266227-69-3 F: C31H45F2N5O5 W: 605.72
T-3256336 is a potent and orally active cIAP1 and XIAP inhibitor with IC50s of 1.3, 200 nM, respectively. T-3256336 show
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