| Bioactivity | T-22 (polyphemusin II with [Tyr5,12,Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV[1][2]. |
| CAS | 147658-54-6 |
| Sequence | Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridge: Cys4-Cys17,Cys8-Cys13) |
| Shortening | RRWCYRKCYKGYCYRKCR-NH2 (Disulfide bridge: Cys4-Cys17,Cys8-Cys13) |
| Formula | C109H164N38O22S4 |
| Molar Mass | 2486.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Masao Masuda, et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850. [2]. Antonella Vitti, et al. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520. |