| Bioactivity | T-10418 is an agonist for G2 accumulation protein (G2A) (also known as G protein-coupled receptor GPR132) with an EC50 of 0.82 μM. T-10418 exhibits a sensitizing effect on mouse primary sensory neurons. T-10418 exhibits good pharmacokinetic characteristics, and no obvious toxicity (at 100 μM) in mouse models[1]. |
| CAS | 1608784-68-4 |
| Formula | C22H20N2O4 |
| Molar Mass | 376.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hernandez-Olmos V, et al., Development of a Potent and Selective G2A (GPR132) Agonist. J Med Chem. 2024 Jun 25. |