Bioactivity | T-1-DOCA ia a EGFR inhibitor, with the IC50 of 56.94 and 269.01?nM for EGFRWT and EGFRT790M, respectively. T-1-DOCA can induces cell apoptosis of HCT-116 cells[1]. |
Name | T-1-DOCA |
Formula | C15H13Cl2N5O3 |
Molar Mass | 382.20 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Eissa IH, et al. Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer. Evol Bioinform Online. 2023;19:11769343231217916. Published 2023 Dec 1. |