Bioactivity | Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1]. | ||||||||||||
Name | Syk-IN-1 | ||||||||||||
CAS | 1491150-77-6 | ||||||||||||
Formula | C18H22N8O | ||||||||||||
Molar Mass | 366.42 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25(20):4642-4647. |