Bioactivity | Sunitinib-d10 is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. | ||||||||||||
Name | Sunitinib-d10 | ||||||||||||
CAS | 1126721-82-1 | ||||||||||||
Formula | C22H17D10FN4O2 | ||||||||||||
Molar Mass | 408.54 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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