| Bioactivity | Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs[1]. |
| Invitro | PROTAC 包含两个通过 Linker 连接的不同配体，其中配体一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白[1]。 |
| Name | Sulfo-NHS-Acetate sodium |
| CAS | 221222-61-3 |
| Formula | C6H6NNaO7S |
| Molar Mass | 259.17 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
Sulfo-NHS-Acetate sodium
CAS: 221222-61-3 F: C6H6NNaO7S W: 259.17
Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of
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