Bioactivity | Sulfamethoxypyridazine-d3 is the deuterium-labeled Sulfamethoxypyridazine (HY-B1387)[1]. Sulfamethoxypyridazine (Kynex) a long-acting dulfonamide[2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | Sulfamethoxypyridazine-d3 |
CAS | 1172846-03-5 |
Formula | C11H9D3N4O3S |
Molar Mass | 283.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Boger W P, et al. Sulfamethoxypyridazine (Kynex) a New Long-Acting Sulfonamide[J]. Antibiotic Med., 1956, 3(6): 378-87. |