Bioactivity | Sulcardine is a multi-ion channel blocker that can reduce INa and ICa with IC50 values of 26.9 µmol/L and 69.2µ mol/L, respectively. Sulcardine has anti-arrhythmic effects[1]. |
Target | IC50: 26.9 µmol/L (INa).IC50: 69.2 µmol/L (ICa). |
Name | Sulcardine |
CAS | 343935-60-4 |
Formula | C24H33N3O4S |
Molar Mass | 459.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. BaiDL,et al. Discovery ofN-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide(sulcardine) as a novel anti-arrhythmic agent. Acta Pharmacol Sin. 2012Sep;33(9):1176-86. |