| Bioactivity | Sulanemadlin (ALRN-6924) is a potent p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research[1]. |
| Name | Sulanemadlin |
| CAS | 1451199-98-6 |
| Sequence | Ac-Leu-Thr-Phe-Ala-Glu-Tyr-Trp-Ala-Gln-Leu-{dAla}-Ala-Ala-Ala-Ala-Ala-{dAla}-NH2(staple between Ala4 and d-Ala11) |
| Shortening | Ac-LTFAEYWAQL(dA)AAAAA(dA)-NH2 (staple between Ala4 and d-Ala11) |
| Formula | C95H140N20O23 |
| Molar Mass | 1930.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Manuel AIVADO, et al. Peptidomimetic macrocycles and uses thereof. WO2018208954A2 |
Sulanemadlin
CAS: 1451199-98-6 F: C95H140N20O23 W: 1930.25
Sulanemadlin (ALRN-6924) is a potent p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2,
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