| Bioactivity | Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2]. |
| In Vivo | Sugammadex (100 mg/kg, IV, once) has a nephroprotective effect when given at the beginning of reperfusion after one hour of ischemic condition on rats[2]. |
| Name | Sugammadex |
| CAS | 343306-71-8 |
| Formula | C72H112O48S8 |
| Molar Mass | 2002.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. de Boer HD, et al. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. Br J Anaesth. 2006 Apr;96(4):473-9. Epub 2006 Feb 7. [2]. Tercan M, Yılmaz İnal F, Seneldir H, Kocoglu H. Nephroprotective Efficacy of Sugammadex in Ischemia-Reperfusion Injury: An Experimental Study in a Rat Model. Cureus. 2021 Jun 17;13(6):e15726. |
Sugammadex
CAS: 343306-71-8 F: C72H112O48S8 W: 2002.15
Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex s
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