Bioactivity | Sudoterb (LL 3858) is an orally active anti-Tuberculosis agent[1]. |
In Vivo | Sudoterb (12.5 mg/kg 和 25 mg/kg,口服,4 周和 8 周) 可有效对抗小鼠的结核分枝杆菌 (M.tuberculosis) 感染[2]。Sudoterb (口服, 小鼠) 显示出 LD50 为 700 mg/kg[2]。 |
Name | Sudoterb |
CAS | 676266-31-2 |
Formula | C29H28F3N5O |
Molar Mass | 519.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Maha A. Elhakeem, et al. Synthesis and anti-mycobacterial evaluation of some new isonicotinylhydrazide analogues. Bulletin of Faculty of Pharmacy, Cairo University. 2015, 53 (1), 45-52 [2]. Protopopova M, et al. In search of new cures for tuberculosis. Med Chem. 2007 May;3(3):301-16. |