Bioactivity | Succinate/succinate receptor antagonist 1 (compound 7a) is a succinate/succinate receptor antagonist. Succinate/succinate receptor antagonist 1 blocks succinate signaling in gingival tissue. Succinate/succinate receptor antagonist 1 inhibits the activation of succinate receptor 1 (SucnRl) with an IC50 value of 20 μΜ. Succinate/succinate receptor antagonist 1 can be used for the research of periodontal disease[1]. |
Name | Succinate/succinate receptor antagonist 1 |
CAS | 2361972-29-2 |
Formula | C17H15N3O |
Molar Mass | 277.32 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. LI, Xin, et al. PERIODONTAL DISEASE THERAPY. WO2019136022. 2020. |