Bioactivity | Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases)[1]. |
CAS | 208264-84-0 |
Sequence | {Suc}-Tyr-Val-Ala-Asp-pNA |
Shortening | {Suc}-YVAD-pNA |
Formula | C31H38N6O12 |
Molar Mass | 686.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. N Margolin, et al. Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. J Biol Chem. 1997 Mar 14;272(11):7223-8. |