| Bioactivity | Subtilisin (Compound proteinase) is a proteolytic enzyme. Subtilisin (Compound proteinase) has catalytic activity in anhydrous dimethyl formamide. Subtilisin (Compound proteinase) can be used as a catalyst for easy coupling between sugars and amino acids[1][2]. |
| Invitro | Subtilisin (Compound proteinase) (30 mg/mL；2.5-7 d) 在无水二甲基甲酰胺中选择性的酰化二糖[1]。Subtilisin (Compound proteinase) (1.8 g；20-72 h) 在无水二甲基甲酰胺中选择性的酰化单糖[1]。Subtilisin (Compound proteinase) 在活化的丁酸三氟乙酯 (TFEB) 存在下，可以酰化黄烷醇异槲皮素 (1) 的 D-葡萄糖[3]。Subtilisin (Compound proteinase) 改善了蛋白质和脂肪酸的溶解度，恢复了多肽和不饱和脂肪酸[4]。 |
| In Vivo | Subtilisin (Compound proteinase) 水解产物 (≤1 kDa 的 meretrix lusoria protamex 水解物，MLPH) (150 mg/kg 和 300 mg/kg；口服；一天一次持续 6 周) 对 ob/ob 小鼠具有抗肥胖和抗高血糖作用[4]。 |
| Name | Subtilisin (Compound proteinase) |
| CAS | 9014-01-1 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Riva S, et al. Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamide[J]. Journal of the American Chemical Society, 1988, 110(2): 584-589. [2]. Philipp M, et al. Inhibition of subtilisin by substituted arylboronic acids. FEBS Lett. 1981 Oct 12;133(1):36-8. [3]. Danieli B, et al. On the regioselectivity of the protease subtilisin towards the acylation of enantiomeric pairs of benzyl and naphthyl glycopyranosides. Part 2[J]. Tetrahedron, 1999, 55(7): 2045-2060. [4]. Kim MJ, et al. Anti-Obesity and Anti-Hyperglycemic Effects of Meretrix lusoria Protamex Hydrolysate in ob/ob Mice. Int J Mol Sci. 2022 Apr 5;23(7):4015. |
Subtilisin (Compound proteinase)
CAS: 9014-01-1 F: W:
Subtilisin (Compound proteinase) is a proteolytic enzyme. Subtilisin (Compound proteinase) has catalytic activity in anh
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