| Bioactivity | Substance P (7-11) is a C-terminal fragment of Substance P which can cause an increase in the intracellular calcium concentration. |
| Invitro | Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM[1]. |
| Name | Substance P (7-11) |
| CAS | 51165-05-0 |
| Sequence | Phe-Phe-Gly-Leu-Met-NH2 |
| Shortening | FFGLM-NH2 |
| Formula | C31H44N6O5S |
| Molar Mass | 612.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Substance P (7-11)
CAS: 51165-05-0 F: C31H44N6O5S W: 612.78
Substance P (7-11) is a C-terminal fragment of Substance P which can cause an increase in the intracellular calcium conc
Data collection：peptidedb@qq.com
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