Bioactivity | Stigmatellin is a antibiotic against yeasts, filamentous fungi and several Gram-positive bacteria, derived from the cell mass of the myxobacterium. Stigmatellin is also a powerful inhibitor of photosynthetic electron transport. Stigmatellin uses various sugars, polysaccharides and acids of the citrate cycle as substrates and inhibits RNA and protein synthesis. Stigmatellin has two different inhibition sites. One is located at the reducing side of Photosystem II. Another one is located at the cytochrome b6/f-complex. Stigmatellin is promising for research of antimicrobial and photosynthesis[1][2]. |
CAS | 91682-96-1 |
Formula | C30H42O7 |
Molar Mass | 514.65 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kunze B, et al. Stigmatellin, a new antibiotic from Stigmatella aurantiaca (Myxobacterales). I. Production, physico-chemical and biological properties. J Antibiot (Tokyo). 1984 May;37(5):454-61. [2]. Oettmeier W, et al. Stigmatellin. A dual type inhibitor of photosynthetic electron transport[J]. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1985, 807(2): 216-219. |