Bioactivity | Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC50 of 1.4±0.3 μM that plays an important role in immune response[1]. |
Target | 1.4±0.3 μM (Spns2-dependent S1P transport) |
Name | Spns2-IN-1 |
Formula | C24H40ClN3 |
Molar Mass | 406.05 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Christopher W Shrader, et al. Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors. Bioorg Med Chem Lett. 2023 Oct 11:96:129516. |