| Bioactivity | Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached[1][2]. | ||||||||||||
| Invitro | Spiramycin (24 hours; 1-1000 μM; T. gondii infected HeLa cells and HeLa cells) treatment reduces the cytotoxicity, and shows anti-Toxoplasma gondii activity, with IC50 values of 189 μM for HeLa cells; and 262 μM for T. gondii-infected HeLa cells[3]. Cell Cytotoxicity Assay[3] Cell Line: | ||||||||||||
| Name | Spiramycin | ||||||||||||
| CAS | 8025-81-8 | ||||||||||||
| Formula | C43H74N2O14 | ||||||||||||
| Molar Mass | 843.05 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Spiramycin
CAS: 8025-81-8 F: C43H74N2O14 W: 843.05
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplas
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