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Sphingosine (d17:1)

CAS: 6918-48-5 F: C17H35NO2 W: 285.47

Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingo
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Bioactivity Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds[1][2][3].
Name Sphingosine (d17:1)
CAS 6918-48-5
Formula C17H35NO2
Molar Mass 285.47
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Stewart ME, et al. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol. 1995 Oct;105(4):613-8. [2]. Hong JH, et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J Invest Dermatol. 2008 Sep;128(9):2166-78. [3]. Choi CH, et al. Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. Arch Pharm Res. 2007 Apr;30(4):502-6.