| Bioactivity | Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syndrome. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively[1]. |
| Name | Spermine Prodrug-1 |
| CAS | 2576358-68-2 |
| Formula | C24H45Cl3N4O5 |
| Molar Mass | 576.00 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mukund P Tantak, et al. Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome. J Med Chem. 2021 Nov 11;64(21):15593-15607. |
Spermine Prodrug-1
CAS: 2576358-68-2 F: C24H45Cl3N4O5 W: 576.00
Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syn
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