| Bioactivity | Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA)[1]. |
| Invitro | Specnuezhenide (0.2-5.0 μg/mL) significantly decreases the mRNA expression of VEGFA induced by CoCl2 as a dose-dependent manner in ARPE-19 cells[2]. |
| Name | Specnuezhenide |
| CAS | 39011-92-2 |
| Formula | C31H42O17 |
| Molar Mass | 686.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Specnuezhenide
CAS: 39011-92-2 F: C31H42O17 W: 686.66
Specnuezhenide ((8E)-Nuezhenide) is isolated fromthe fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can
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