| Bioactivity | Spantide I TFA, a substance P analog, is a selective NK1 receptor antagonist, with Ki values of 230 nM and 8150 nM for NK1 and NK2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation[1][2][3]. |
| Name | Spantide I TFA |
| Shortening | {D-Arg}-PKPQQ-{D-Trp}-F-{D-Trp}-LL-NH2 |
| Formula | C77H109F3N20O15 |
| Molar Mass | 1611.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |