| Bioactivity | Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of human leukemia cell HL-60 and colon cancer cell LS-174T, with IC50 of 8-100 μM. Sp-8-Cl-cAMPS activates the protein kinases cAKI and cAKII, with Ka of 0.25 and 3.2 μM[1]. |
| CAS | 142754-28-7 |
| Formula | C10H11ClN5O5PS |
| Molar Mass | 379.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yokozaki H, et al., Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells. Cancer Res. 1992 May 1;52(9):2504-8. |
Sp-8-Cl-cAMPS
CAS: 142754-28-7 F: C10H11ClN5O5PS W: 379.72
Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of hum
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.