Bioactivity | Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease[1]. |
Name | Sortilin antagonist 1 |
CAS | 2691846-93-0 |
Formula | C20H24N2O4 |
Molar Mass | 356.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kjoelby, Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss. WO2022074119. 2022. |