| Bioactivity | Sorafenib-d3 is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. | ||||||||||||
| Name | Sorafenib-d3 | ||||||||||||
| CAS | 1130115-44-4 | ||||||||||||
| Formula | C21H13D3ClF3N4O3 | ||||||||||||
| Molar Mass | 467.84 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109. |
Sorafenib-d3
CAS: 1130115-44-4 F: C21H13D3ClF3N4O3 W: 467.84
Sorafenib-d3 is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM fo
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